Resolving enantiomers using the optical angular momentum of twisted light

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Resolving enantiomers using the optical angular momentum of twisted light

Circular dichroism and optical rotation are crucial for the characterization of chiral molecules and are of importance to the study of pharmaceutical drugs, proteins, DNA, and many others. These techniques are based on the different interactions of enantiomers with circularly polarized components of plane wave light that carries spin angular momentum (SAM). For light carrying orbital angular mo...

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Many naturally occurring biomolecules, such as amino acids, sugars and nucleotides, are inherently chiral. Enantiomers, a pair of chiral isomers with opposite handedness, often exhibit similar physical and chemical properties due to their identical functional groups and composition, yet show different toxicity to cells. Detecting enantiomers in small quantities has an essential role in drug dev...

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ژورنال

عنوان ژورنال: Science Advances

سال: 2016

ISSN: 2375-2548

DOI: 10.1126/sciadv.1501349